Rathke’s cleft cyst: A case report of recurrence and spontaneous involution

•Rathke’s cleft cyst is a benign lesion.•Most Rathke’s cleft cysts are successfully managed conservatively.•Spontaneous involution of Rathke’s cleft cyst can occur following initial resection and recurrence.

Rathke’s cleft cysts (RCC) are sellar lesions that typically remain asymptomatic throughout life. Symptomatic patients present with headache, visual disturbance and/or pituitary dysfunction and are treated with resection. We present a 61-year-old woman diagnosed with RCC which was resected twice then recurred before undergoing spontaneous resolution. RCC are often managed without surgical intervention. Some of these lesions may spontaneously resolve without surgical intervention while others may become symptomatic. In patients with asymptomatic recurrent RCC conservative management is recommended. Spontaneous involution may occur following initial resection and recurrence of RCC.