Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3059632 | Journal of Clinical Neuroscience | 2014 | 4 Pages |
Abstract
Temozolomide (TMZ), an alkylating agent, is widely used for treating high-grade gliomas. TMZ has been reported to cause secondary myelodysplastic syndrome and acute myeloid leukemia. However, TMZ-related acute lymphoblastic leukemia is rare. Here we describe a 54-year-old woman with glioblastoma multiforme, who developed precursor-B acute lymphoblastic leukemia with translocation (4;11)(q21;q23) after 15 months of TMZ treatment.
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Neurology
Authors
Kuan-Nien Chou, Yu-chieh Lin, Ming-Ying Liu, Ping-Ying Chang,