Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3060448 | Journal of Clinical Neuroscience | 2012 | 4 Pages |
Abstract
Cerebral aneurysms of traditional animal models are usually too small to be imaged in vivo. A novel rat model induced by ligation of the unilateral common carotid artery and contralateral pterygopalatine and external carotid arteries was investigatid. To evaluate the morphological changes of the cerebral arteries, synchrotron radiation angiography was utilised at 1 month, 2 months and 3 months after induction. Cerebral aneurysms and expansion of anterior cerebral arteries in these rats were identified when the animals were alive. This novel model is useful for cerebral aneurysm research.
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Neuroscience
Neurology
Authors
Jun Cai, Chuan He, Falei Yuan, Lujia Chen, Feng Ling,