Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3071930 | Neurocirugía | 2006 | 7 Pages |
Abstract
Familial glioblastoma with metachronous presentation is an exceptional disorder. These tumors show special therapeutic implications due to the limitations of radiotherapy once the patient has already irradiated. A variety of non-specific mutations have been found in these patients but true characterization of this disorder remains unclear and will be based on further genetic studies. We present a clinical report on a patient harbouring a familial and metachronous glioblastoma. The main aspects of this entity are reviwed.
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Authors
B. Iza, O. Mateo-Sierra, F. Ruiz-Juretszke, J. Garbizu, R. Carrillo, J. Guzmán de Villoria,