Síndrome de Moyamoya en paciente con síndrome de Down y alteraciones asociadas

MMS is three times more frequent in DS patients than in general population and is usually associated with deficiency of protein C and S, hyperthyroidism worsens stenosis. The treatment may be medical but in children is preferred bypass surgery by risk of new neurological events since otherwise the prognosis is poor. We recommend evaluate for MMS in all patients with DS and stroke.