Assessing the Impact of Ease of Administration and Tolerability on Treatment Choices in Parkinson's Disease

Historically Parkinson's disease (PD) has been treated primarily with oral agents, with patients learning quickly that their clinical response is tied closely to their level of medication compliance. Studies, however, have found that compliance is less than ideal, and erratic medication consumption is commonplace. When prescribing antiparkinsonian therapies, the clinician should consider ease of administration, tolerability, and efficacy, along with other factors that are likely to contribute to optimal compliance by the patient.