Intravenous Ketogenic Diet Therapy for Treatment of the Acute Stage of Super-Refractory Status Epilepticus in a Pediatric Patient

BackgroundA ketogenic diet has been used successfully to treat intractable epilepsy. However, the role of early intravenous initiation of ketogenic diet in the acute phase of super-refractory status epilepticus is not well-described.MethodsAn intravenous ketogenic diet was administered to a boy with super-refractory status epilepticus. At 24 hours after intravenous ketogenic diet, moderate ketosis appeared, and thiamylal was successfully weaned at 70 hours after admission.ResultsAn intravenous ketogenic regimen led to subsequent ketosis and seizure control in a child with super-refractory status epilepticus.ConclusionEarly induction of ketosis may be a novel strategy to effectively treat super-refractory status epilepticus. Although there are few data regarding the early use of intravenous ketogenic diet in the treatment of super-refractory status epilepticus, it may be considered an alternative option.