| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3086312 | Pediatric Neurology | 2007 | 4 Pages |
Abstract
A 16-month-old girl presented with herpes simplex virus type 1 encephalitis with involvement of bilateral parietofrontal lobes, left thalamus and cerebellum. She was treated with intravenous acyclovir. As her condition deteriorated, high-dose methylprednisolone was administered, resulting in remarkable improvement. This case suggests considering a short course of high-dose steroid therapy in severe herpes simplex encephalitis when there is clinical and radiologic deterioration in spite of appropriate antiviral therapy and decreasing viral load in the cerebrospinal fluid.
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Authors
Banan Musallam, Israel Matoth, Dana G. Wolf, Dan Engelhard, Diana Averbuch,