Cavernomatose évolutive radio-induite de l'adulte

Cerebral cavernomas (CC) are cerebral vascular malformations affecting 0.4 to 0.8 % of the population. Radiation-induced CC have exceptionally been reported, the majority in children. We report the case of a patient irradiated at the age of 40 for a right frontal astrocytoma presenting multiple CC more than 20 years after irradiation. We have identified 146 cases reported so far, including 23 adults. Radiation-induced CC are often multiple and would have a higher bleeding risk than sporadic or familial CC. A better definition of fields and dosages and the reduction of prophylactic irradiation may explain the decrease in the number of reported cases.