Article ID Journal Published Year Pages File Type
3087351 Pratique Neurologique - FMC 2012 7 Pages PDF
Abstract
Amyloid angiopathy is probably the most frequent non-hypertensive cerebral microangiopathy. Because of its close relationships with Alzheimer's disease, its definition and diagnosis may be difficult. Its clinical and radiological phenotype is quite variable. Other forms of non-hypertensive cerebral microangiopathies have been reported lately with the development of brain MRI. Most of them are of genetic origin. The most frequent, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), is a monogenic disease with eventual devastating clinical consequences affecting young patients. Other forms, particularly of genetic origin, are regularly reported.
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