Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3096208 | World Neurosurgery | 2013 | 8 Pages |
Abstract
Malignant vestibular nerve tumors are extremely rare; only 18 cases have been reported in the literature. Our patient is the sixth pathologically confirmed case of malignant transformation after radiosurgery, supporting the contention that radiosurgery itself may play a causative role in transformation. In a histologically benign lesion, the presence of an elevated MIB-1 labeling index may predispose toward malignant transformation in the setting of adjuvant radiosurgery.
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Authors
Vijay Yanamadala, Richard W. Williamson, David J. Fusco, Jennifer Eschbacher, Peter Weisskopf, Randall W. Porter,