Early versus Delayed Endoscopic Surgery for Carpal Tunnel Syndrome: Prospective Randomized Study

ObjectiveTo compare the effects of early versus delayed endoscopic surgery in patients with moderately severe carpal tunnel syndrome (CTS).MethodsThe study included 100 patients with CTS. Investigations performed before surgery excluded secondary causes. Patients with moderately severe CTS (grade 3–4) were randomly assigned. Bland’s neurophysiologic grading scale for CTS was used to assess the patients. Patients underwent an endoscopic carpal tunnel release using an indigenously designed instrument.ResultsFollowing a course of conservative treatment, surgical treatment was offered in two groups: early surgery (n = 51; <1 week after diagnosis) and delayed surgery as per the usual waiting list (n = 49; >6 months after diagnosis). Improvement in both groups was significant (P < 0.001). When both groups were compared, improvement was better for the early surgery group (P < 0.001; confidence interval 6.35–9.12).ConclusionsOn the basis of this study, early endoscopic surgery is proposed in patients with moderately severe CTS.