| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3099907 | Journal of Traditional and Complementary Medicine | 2012 | 4 Pages |
Abstract
In vitro anti-allergic screening of medicinal herbal extracts revealed that the 80% acetone extract of the rhizome of Kadsura coccinea inhibited nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ (IFN-γ) activated murine macrophage like cell line, RAW264.7. Further fractionation of the EtOAc extract led to the isolation of one new 3,4-seco-lanostane type triterpene named kadsuracoccin acid A (1) together with two known triterpenes anwuweizonic acid (2) and neokadsuranic acid B (3). Compounds 1 − 3 did not exhibit any inhibitory activities for NO production and IFN-γ activation.
Keywords
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Complementary and Alternative Medicine
Authors
Hai-Xia Li, Jie Fan, Wen Hu, Chao Wang, Susumu Kitanaka, He-Ran Li,