Granulocyte Colony-stimulating Factor—producing Mucoepidermoid Carcinoma of the Mandibular Gingiva

Mucoepidermoid carcinoma comprises approximately 35% of all malignancies of major and minor salivary glands. Histopathologically, these are classified as low, intermediate, or high-grade tumours, where prognosis depends on the grading. This report is of a patient with mucoepidermoid carcinoma of the mandibular gingiva that produced granulocyte colony-stimulating factor, in whom granulocyte colony-stimulating factor production by the tumour lead to rapid local recurrence as well as distant metastasis.