Report of a case of Zimmermann–Laband syndrome with new manifestations

Zimmermann–Laband syndrome is a rare disorder characterized by gingival fibromatosis, abnormalities of the nose and/or ears, absence and/or hyperplasia of the nails or terminal phalanges of the hands and feet, hyperextensibility of joints, hepatosplenomegaly, mild hirsutism and mental retardation. The syndromic characteristics of Zimmermann–Laband syndrome are highly variable and complicated. This paper described a patient with Zimmermann–Laband syndrome with new manifestations and discusses the possible underlying genetic mechanisms.