| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3135118 | International Journal of Oral and Maxillofacial Surgery | 2006 | 4 Pages |
Abstract
The present study investigated induction of apoptosis in NB-1 oral carcinoma cells by paclitaxel and the expression of Bcl-2 and Bax in relation to this apoptotic cell death. Paclitaxel induced apoptotic cell death in NB-1 cells in a dose- and a time-dependent manner. The present results suggest that paclitaxel can induce apoptosis of NB-1 cells, which may be mediated by down-regulation of Bcl-2 together with up-regulation of Bax.
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Authors
M. Nonaka, H. Ikeda, A. Fujisawa, M. Uehara, T. Inokuchi,