Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3146779 | Journal of Endodontics | 2015 | 6 Pages |
Abstract
IL-6 and CRP messenger RNA are constitutively expressed in periodontal ligament and up-regulated in ALEOs along with higher protein levels. Given their pleiotropic effects, IL-6 and CRP protein levels in apical tissues might partially explain the development and progression of ALEOs as well as potentially asymptomatic apical periodontitis-associated systemic low-grade inflammation.
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Authors
Mauricio DDS, Andrea DDS, MarÃa José DDS, Montserrat DDS, MSc, Rolando PhD, Samantha DDS, MSc, PÃa DDS, Rodolfo DVM, PhD, Jocelyn Licentiate in Biochemistry, Pablo Ahumada-Montalva, Marcela DDS, MSc, PhD,