Article ID Journal Published Year Pages File Type
3148126 Journal of Endodontics 2010 6 Pages PDF
Abstract
These results suggest that TNF-α and IL-1α up-regulate HBD-2 expression in HDP cells through the PKC, JNK MAPK, p38, ERK, NF-κB, and AMPK pathways. Thus, the induction of hBD-2 by proinflammatory cytokines might up-regulate the pulpal host immune defense system.
Keywords
Related Topics
Health Sciences Medicine and Dentistry Dentistry, Oral Surgery and Medicine
Preview
Effect of Proinflammatory Cytokines on the Expression and Regulation of Human Beta-Defensin 2 in Human Dental Pulp Cells
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