Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3148211 | Journal of Endodontics | 2013 | 7 Pages |
Abstract
Simvastatin may alleviate periapical lesions by enhancing FoxO3a activity to suppress the synthesis of Cyr61 in osteoblasts. Moreover, the downstream effector mechanism of Cyr61 may involve CCL2 production and macrophage recruitment.
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Authors
Li-Deh DDS, PhD, Sze-Kwan DDS, PhD, Yueh-Ling DDS, Sang-Heng DDS, PhD, Chi-Yuan DDS, DMSc, Kuo-Liang MS, Eddie Hsiang-Hua DDS, MS, Hsiang DDS, Ming-Shu DDS, Juo-Song DDS, MS,