| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3153783 | Journal of Oral and Maxillofacial Surgery | 2013 | 11 Pages |
Abstract
Gene-modified tissue-engineered bone grafts have greater osteogenic potential than single tissue-engineered bone and single bioactive glass ceramic graft. Ex vivo Ad-BMP-2 transfer to periosteal-derived cells can increase bone formation in critical-size bone defects. Further studies are needed to determine if modified engineered cells can be developed for safe and effective clinical applications.
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Authors
Mingxia MD, Wanye PhD, Ketao PhD, Zuoqing PhD, Huahai MD, Fengcai MD,