Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3156077 | Journal of Oral and Maxillofacial Surgery | 2014 | 10 Pages |
Abstract
The biomaterial implants using rhBMP-2 and LZ-8 had good biocompatibility and osteogenetic capabilities in the rabbit sinus model. Bone healing in rhBMP-2-treated defects was excellent and showed a significant difference compared with LZ-8. However, LZ-8-treated defects also exhibited bone regeneration, and this traditional Chinese medicine may possess osteogenic potential. Further investigations of the mechanism and application of this protein in osteogenesis are needed.
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Authors
Hsiu-An DDS, Chia-Yu MS, Jan-Show MS, Li-Hsiang MS, Chen-An Lu, Keng-Liang PhD,