Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3156644 | Journal of Oral and Maxillofacial Surgery | 2012 | 5 Pages |
Abstract
Primary small cell neuroendocrine carcinoma of the paranasal sinuses is an extremely rare and distinctive tumor with aggressive clinical behavior. We report on a patient who had a small cell neuroendocrine carcinoma of the ethmoid sinus with invasion of the upper aspect of the right maxillary sinus and medial aspect of the right orbit. After 2 cycles of chemotherapy that were unsuccessful, he underwent radiotherapy with complete tumor remission. Local recurrence was not identified after 11 months of follow-up; however, distant metastasis developed 2 months after radiotherapy. The natural history, pathologic features, and choice of therapy for this rare neoplasm are discussed, along with a review of the published data.
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Authors
Guang Han, Zhaohua Wang, Xiaofang Guo, Mingwei Wang, Huijing Wu, Dong Liu,