Keratocystic Odontogenic Tumor (Odontogenic Keratocyst): Preliminary Retrospective Review of Epidemiologic, Clinical, and Radiologic Features of 261 Lesions From University of Turin

PurposeTo analyze and discuss the demographic, clinical, and surgical aspects of 261 surgically treated keratocystic odontogenic tumors.Patients and MethodsA retrospective review was performed of all cases of treated keratocystic odontogenic tumors. Statistical analysis was used to search for associations among age, presenting symptoms, location, dimension, and locularity.ResultsKeratocystic odontogenic tumors most commonly occurred in patients in the third and fourth decades of life. The ratio of males to females was 2:1. The mandibular angle region was the most frequently involved site. Significant associations were found between multilocular lesions and lesions larger than 31 mm (P < .00000005), a mandibular site and larger lesions (P < .05), patients younger than 41 years old and multilocular lesions (P < .05), and younger patients and larger lesions (P < .00005).ConclusionIt is likely that most multilocular, larger (and probably aggressive) lesions are found in patients younger than 41 years of age.