A medical elaboration on von Willebrand disease with its dental management

Objectivevon Willebrand disease (vWD) is the most common type of autosomally inherited bleeding disorder representing a range of quantitative and qualitative pathologies of the adhesive glycoprotein, von Willebrand factor (vWF). Since symptoms are often mild, a significant majority of patients remain undiagnosed.MethodA review from the literature which imparts the knowledge on background, pathophysiology, classification, diagnostic measures and treatment modalities of this fatal bleeding disorder.ResultsWith all forms of vWD, however, bleeding episodes can be severe and may require treatment.ConclusionsA primary care physician should play a role in recognizing the signs and symptoms of vWD and in referring patients for proper management. The treatment of bleeding in vWD involves the use of desmopressin and plasma-derived vWF concentrates and a variety of adjunctive agents.