Familial mucocutaneous candidiasis - a case report

Chronic mucocutaneous candidiasis is an immune-deficiency disorder primarily due to T- cell dysfunction characterized by persistent candidal infection of mucous membrane, skin, scalp and nails. A familial occurrence has been reported in some instances suggesting a genetic predisposition. Chronic mucous membrane candidiasis has an onset in infancy or childhood; the primary affected site is the oral cavity; however, lesions may occur on trunk, hands, feet and scalp. This paper describes two siblings with candidial infection of the oral mucosa associated with cutaneous bacterial infection.