Wilson's Disease - A Case Report with Current Status and Management

Wilson's disease (WD) is an autosomal recessive inherited disorder of copper metabolism. The condition is characterized by excessive deposition of copper in the liver, brain, and other tissues. The worldwide incidence rate is 10-30 million cases per year. The diagnosis is made by measuring sérum ceruloplasmin, urinary copper excretion, and hepatic copper content, as well as the detection of Kayser-FIeischer rings. The mainstay of therapy is copper chelators like D-Pencillamine and Trientine for reduction in body copper to sub-toxic levels. This case report tries to give an insight into the clinical features, diagnosis and management of WD with special emphasis on the dental management that may be taken during the treatment of the same.