Systemic Lupus Erythematosus and Discoid Lupus Erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disorder of unknown etiology that affects numerous organ systems including the renal, cardiovascular, gastrointestinal, and central and peripheral nervous systems. The practicing oral and maxillofacial surgeon needs to understand the potential complications of SLE and the alterations in treatment protocols which would be necessary to safely treat a patient with SLE. This article outlines the disease process, prevalence and presentation, and specific variants, and discusses treatment regimens available for incorporation into current practice.