Article ID Journal Published Year Pages File Type
3169339 Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 2007 12 Pages PDF
Abstract

ObjectiveThis article shows the in vitro and in vivo characterization of a new biomimetic treatment developed to enhance the osseointegration of titanium dental implants.Study designA novel biomimetic treatment of titanium was developed. Its physicochemical properties and biologic and in vivo performance were considered and studied. Mineralization capability was assessed by soaking test in simulated body fluid solution, and cytocompatibility was assessed using osteoblast-like MG63 cell culture. Histomorphometric analysis was performed at 3 time points using a sheep animal model.ResultsIn vitro tests confirmed the biomimetic potential of the considered novel treatment. Histomorphometric analysis indicated its potential for rapid and good-quality osseointegration.ConclusionThe in vitro and in vivo test results indicated that the proposed novel treatment possesses a significant potential to increase the rate of osteointegration of titanium for endosseous dental implants.

Related Topics
Health Sciences Medicine and Dentistry Dentistry, Oral Surgery and Medicine
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