Mięsak gładkokomórkowy - niezwykle rzadki nowotwór złośliwy części nosowej gardła

Malignant nasopharygeal neoplasms are relatively rare. Anaplastic nasopharyngeal carcinoma is the most common and the most malignant one. In this paper, we present a case of 56-year old patient with high-grade leiomyosarcoma of nasopharynx. The final diagnosis was achieved by using immunohistochemical methods - SMA (+), Caldesmon (+/−), Desmin (+/−), bcl 2 (+/−), EMA (−), S-100 (−), CD 34 (−), MIB 1 - 70% cells. The patient was successfully treated with radical radiotherapy IMRT technique (total dose 7000 cGy in 7 weeks). Currently, the patient has no symptoms and signs of the disease (oncological follow-up; CT imaging, PET-CT). This case is the first nasopharyngeal leiomyosarcoma reported in Poland, and probably the second one in the world.