Izolowany przerzut raka piersi do ślinianki przyusznej jako pierwszy objaw późnego nawrotu choroby nowotworowej. Czynniki prognostyczne

Parotid gland metastases from distant malignant tumors are uncommon (0.16-4%). The distinction between primary and metastatic tumors in salivary gland is of special importance for therapy and prognosis. For the treatment of this metastasis, parotidectomy, radiation, chemotherapy, and hormone therapy were performed. The authors presented the case of distant metastasis to the parotid gland; a 59-year-old woman with breast cancer and metastases to the parotid gland 12 years after surgery. Because immunohistochemical analysis in our case had revealed the tumor to be positive for estrogen and progesterone receptors we continued to administer postoperatively hormonotherapy. The prognosis of patients presenting with metastatic deposits in parotid gland from a distant primary tumor is usually poor. The long-term prognosis is influenced by the histological type, location, and staging of the primary tumor type and steroid receptors - positive and HER2 overexpression. Adjuvant hormonotherapy is an effective treatment, which prolongs survival in women with hormone receptor-positive breast cancer.