Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3181990 | Actas Dermo-Sifiliográficas | 2006 | 4 Pages |
Abstract
Pemphigus vulgaris is a potentially fatal autoimmune bullous disease. High doses of immunosuppressive drugs are used in managing severe cases of pemphigus. Rituximab, an anti-CD20 monoclonal antibody, has proven to be effective in patients with refractory pemphigus vulgaris and pemphigus foliaceus. We review cases of pemphigus vulgaris and pemphigus foliaceus not associated with lymphoma that were treated with rituximab, and we report a new case of severe refractory pemphigus vulgaris successfully treated with rituximab.
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Authors
Gerard Pitarch, José L. Sánchez-Carazo, José Pardo, Arantxa Torrijos, Elena Roche, José M. Fortea,