Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3187978 | Annales de Dermatologie et de Vénéréologie | 2011 | 4 Pages |
Abstract
The clinical and histological features of this autoimmune bullous disease were evocative of BP, despite the absence of any formal proof. Radio-induced BP is extremely rare, with only 28 cases being described to date in the literature. The trigger mechanism is poorly understood; radiotherapy appears to cause changes in the antigenic properties of proteins in the dermal-epidermal junction resulting in production of autoantibodies. The radio-induced nature of BP does not affect therapeutic response. The case we report is novel in terms of both generalisation of the eruption and mucosal involvement.
Keywords
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Authors
N. Srifi, S. Benomar, N. Zaghba, S. Qasmi, K. Senouci, B. Elgueddari, B. Hassam, N. Ismaili,