Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
318989 | European Neuropsychopharmacology | 2010 | 4 Pages |
Abstract
Two serotonin 2A receptor (HTR2A) SNPs recently reported to be associated with antidepressant treatment response in STAR⁎D (rs7997012; rs1928040) were analyzed for association with treatment response in two independent Caucasian samples of patients with a Major Depressive Episode. In the combined sample (n = 637) SNP rs7997012 was significantly associated with remission after five weeks providing first replicative support for the initial finding, with, however, an inverse allelic association as compared to the STAR⁎D sample.
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Authors
Susanne Lucae, Marcus Ising, Sonja Horstmann, Bernhard T. Baune, Volker Arolt, Bertram Müller-Myhsok, Florian Holsboer, Katharina Domschke,