| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3190322 | Annales de Dermatologie et de Vénéréologie | 2006 | 4 Pages |
Abstract
This patient presented the characteristics of primary cutaneous CD8+ epidermotropic cytotoxic T-cell lymphoma described by Berti. The clinical findings in most cases consist of nodular and ulcerative cutaneous lesions. Histologically, the cutaneous infiltrate is composed of pleomorphic lymphocytes with marked and constant epidermotropism. Immunohistochemistry shows lymphocytes expressing a CD8+ phenotype and cytotoxic proteins, which probably accounts for the local and systemic aggressiveness of the disease, as well as the angiodestructive nature of the infiltrate and the necrotic lesions.
Related Topics
Health Sciences
Medicine and Dentistry
Dermatology
Authors
E. Poszepczynska-Guigné, M. Jagou, J. Wechsler, M.T. Dieng, J. Revuz, M. Bagot,