Article ID Journal Published Year Pages File Type
3192045 Annals of Allergy, Asthma & Immunology 2010 7 Pages PDF
Abstract
In patients with allergic rhinitis or intermittent asthma, methacholine or AMP-induced changes in FVC are not significantly related to the presence or level of plateau. Furthermore, these 2 constituents of the concentration-response curve can be modified independently by a proinflammatory stimulus. These results suggest that the bronchoconstrictor-induced change in FVC cannot be used as a surrogate estimation of the level of plateau.
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