Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3192176 | Annals of Allergy, Asthma & Immunology | 2011 | 7 Pages |
Abstract
These results support the importance of MMP-9 and TIMP-1 expression in nasal polyp formation. The decreased expression of TIMP-1 in AS patients may promote the effects of MMP-9 expression and thus contribute to tissue remodeling and inflammatory changes. This finding may lead to further understanding of disease severity and resistance to treatment in this group of patients, as well as the pathogenesis of nasal polyps.
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Authors
Pamela A. MD, Rohit K. MD, Raeful MD, Samantha MD, Vijay MD, Todd T. MD,