Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3192522 | Annals of Allergy, Asthma & Immunology | 2010 | 12 Pages |
Abstract
Bradykinin is the mediator of swelling in types I and II HAE and is overproduced because of a deficiency in C1 inhibitor. Inhibition of bradykinin formation by novel agents can provide targeted therapeutic approaches that address the pathophysiologic abnormalities.
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Authors
Allen P. MD, Kusumam PhD,