Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3194998 | Clinics in Dermatology | 2008 | 6 Pages |
Abstract
Efalizumab is a humanized monoclonal antibody directed against the CD11a subunit of the lymphocyte function-associated antigen 1. It has been approved for the treatment of moderate-to-severe plaque psoriasis. Efalizumab has been shown in several clinical trials to be effective and well tolerated in the treatment of patients with moderate-to-severe psoriasis. The safety profile of continuous therapy with efalizumab-as far as it is currently available-is favorable. Mode of action, pharmacological profile, clinical indications and efficacy, safety, and tolerability as well as practical considerations of efalizumab are reviewed in this article.
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Authors
Michael P. MD,