Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3195180 | Clinics in Dermatology | 2006 | 4 Pages |
Abstract
Herpes gestationis, coined by Milton in 1872, or gestational pemphigoid is the most clearly characterized dermatosis of pregnancy. It is a rare vesiculo-bullous eruption that develops during the last trimester or even postpartum and creates severe pruritus. Its etiology is unknown, but it is considered as an autoimmune-mediated dermatosis closely related to the pemphigoid group. Herpes gestationis is associated with a positive C3 deposition along the base of the epidermis in salt–split skin, with increased frequency of HLA-DR3 and also the combination DR3 and DR4. It has a high risk of prematurity and disappears in the postpartum period within weeks or months.
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Authors
Abdul-Wahab S. Al-Fouzan, Ibrahim Galadari, Isam Oumeish, Oumeish Y. Oumeish,