Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3196289 | Dermatologica Sinica | 2016 | 4 Pages |
Abstract
Two female patients presented with bullous cutaneous lupus on sun-exposed areas and synovitis, and tested positive for antinuclear antibodies, anti-Smith (anti-Sm), anti-dsDNA, and low complement levels. Case 2 also suffered oral ulcers. Thus, diagnoses of bullous systemic lupus erythematosus (BSLE) were made. Both patients responded distinctly to Tripterygium wilfordii polyglycosidium (T2; 60 mg/day) combined with oral prednisone (30–40 mg/day), which showed efficacy in 1–2 weeks and produced no side effects. Therefore, T2 combined with low-dose corticosteroids may be an effective and highly tolerable alternative for treating BSLE.
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Authors
Guangping Wang, Caimei Wang, Xiulian Xu, Hong Jia,