Article ID Journal Published Year Pages File Type
3197064 International Journal of Women's Dermatology 2016 8 Pages PDF
Abstract

Dermatologists should be aware that autoantibody formation may occur after the initiation of biologic therapy. This phenomenon has been referred to as immunogenicity and biologic fatigue. Because of this, patients may experience loss of clinical efficacy to a particular drug. To combat this phenomenon, low-dose immunomodulators may be used in hopes of preventing autoantibodies. We review the current literature and provide a basic treatment algorithm for patients with moderate to severe psoriasis.

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Health Sciences Medicine and Dentistry Dermatology
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