| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3197669 | Journal of Allergy and Clinical Immunology | 2014 | 20 Pages |
Abstract
The mast cell-intrinsic clockwork, entrained by humoral factors from the adrenal gland, primarily contributes to the temporal regulation of IgE/mast cell-mediated allergic reactions. Our results reveal a novel regulatory mechanism for IgE-mediated mast cell responses that might underlie the circadian pathophysiology in patients with allergic diseases.
Keywords
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Immunology
Authors
Yuki Nakamura, Nobuhiro PhD, Kayoko Ishimaru, Mutsuko PhD, Takako PhD, Yu PhD, Ryohei MD, PhD, Hideoki MD, PhD, Ko MD, PhD, Shigenobu PhD, Chiharu PhD, Atsuhito MD, PhD,