Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3197916 | Journal of Allergy and Clinical Immunology | 2013 | 15 Pages |
Abstract
Our findings demonstrate that differentiated TH2 cells can resist IL-27-induced reprogramming toward TH1 cells by downregulating STAT1 phosphorylation and likely explain why the CD4+ T cells of asthmatic patients are resistant to IL-27-mediated inhibition.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Zhihong MD, PhD, Shanze MD, PhD, Nkiruka MPH, MD, Yapeng PhD, Jessie PhD, Xiaopeng PhD, Patricia MS, Vijaya MD, PhD, Eugene MD, Rohit MD, Rafeul MD, PhD, Anita MD, Hong Wei MD, Yonghua MD, PhD, Meiling MD, Chunxue MD, PhD, Hua MD, PhD,