| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3197917 | Journal of Allergy and Clinical Immunology | 2013 | 27 Pages |
Abstract
Rapidly exposing MCs to progressively increasing amounts of antigen can both enhance the internalization of antigen-specific IgE on the MC surface and also desensitize these cells in an antigen-specific manner in vivo and in vitro.
Keywords
FITCMast cell protease 1Mcpt-1BMCMCStat6DNPOVAPMCPGD2HSAMFIIgEPSA2,4-dinitrophenylhuman serum albuminpassive systemic anaphylaxisAnaphylaxisOvalbuminbasophilrapid desensitizationReceptor internalizationBone marrow–derived cultured mast cellPeritoneal mast cellfluorescein isothiocyanateDegranulationMast cellSignal transducer and activator of transcription 6mean fluorescence intensityAntigenProstaglandin D2Desensitization
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Authors
Tatsuya DVM, PhD, Eon J. MD, PhD, Mindy DMSc, Janet PhD, Stephen J. MD,