Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3198178 | Journal of Allergy and Clinical Immunology | 2013 | 17 Pages |
Abstract
A rapid desensitization approach with anti-FcεRIα mAb safely desensitizes mice to IgE-mediated anaphylaxis by inducing mast cell anergy and later removing all mast cell IgE. Rapid desensitization with an anti-human FcεRIα mAb may be able to prevent human IgE-mediated anaphylaxis.
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Authors
Marat V. PhD, Zeynep Yesim MD, Richard T. Strait, Durga MS, Kevin BS, Ian PhD, Suzanne C. PhD, Fred D. MD,