| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3198191 | Journal of Allergy and Clinical Immunology | 2013 | 16 Pages |
Abstract
We have identified the central roles of IL-17A and neutrophils in the pathogenesis of fibrosis in experimental hypersensitivity pneumonitis. We have also established that nonlymphocytic innate immune cells, specifically neutrophils and monocytes/macrophages, rather than TH17 lymphocytes, are the predominant source of IL-17A in experimental hypersensitivity pneumonitis.
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Authors
Simon A. BSc, Bertus MBChB, FRCP (UK), PhD, Danielle MSc, Heather V. BSc, Abrar BSc, Kerri MD, FRCPC, Carol MLT, Kimberly-Ann R. MSc, Tina BSc, David PhD, FRCS, Margaret M. MBChB, FRCPC, PhD,