| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3198369 | Journal of Allergy and Clinical Immunology | 2012 | 12 Pages |
Abstract
We identified RGS2 as a potent modulator of AHR and a potential novel therapeutic target for asthma.
Keywords
RGSG protein–coupled receptorsAirway smooth muscle contractionPI3KGPCRsASMmAChRERKAHRAsthmaCa2+ mobilizationRegulator of G protein signalingAirway smooth musclePhosphatidylinositol 3-kinaseGrowth mediumKnockout micewild-typeAirway hyperresponsivenessextracellular signal-regulated kinaseMuscarinic receptor
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Authors
Yan MD, PhD, Haihong MD, PhD, Hoai MD, Shuping MS, Abdo PhD, Reynold A. MD, Dennis W. PhD, Peter W. PhD, Thomas B. MD, Yaping PhD,