Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3198494 | Journal of Allergy and Clinical Immunology | 2012 | 8 Pages |
Abstract
IgM antibodies appear to be microbiologically and clinically protective and might thus attenuate the infectious consequences of a lack of production of other immunoglobulin isotypes in patients with HIgM syndrome. Polyvalent IgG replacement therapy might not fully compensate for IgM deficiency. It might thus be worth adapting long-term antimicrobial prophylactic regimens according to the underlying B-cell immunodeficiency phenotype.
Keywords
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Authors
Romain MD, MPH, PhD, Samer MD, PhD, Nizar MD, MSc, Julien MD, MSc, Pauline MD, MPH, Yasmine BS, Gaëlle MD, Vincent MD, Nathalie MD, Kamila MD, Caroline MD, Fabienne MD, Fabrice MD, Raphaële MD, Isabelle MD, Olivier MD, PhD, Alexandra MD, Agathe MD,