| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3198500 | Journal of Allergy and Clinical Immunology | 2012 | 17 Pages |
Abstract
PU.1 basally transactivates the CIITA pI promoter in DCs by functioning as a monomeric transcription factor and by affecting histone modification, resulting in the subsequent expression and function of MHC class II.
Keywords
PU.1BMDCIRFGAPDHPDCCDCFITCCREBCIITASmall interfering RNAsiRNAStat1Electrophoretic mobility shift assaychromatin immunoprecipitationDendritic cellPlasmacytoid dendritic cellBone marrow–derived dendritic cellconventional dendritic cellDendritic cellsEMSA یا electrophoretic mobility shift assay interferon regulatory factorfluorescein isothiocyanatesignal transducer and activator of transcription 1CHiPclass II transactivatorglyceraldehyde-3-phosphate dehydrogenase
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Authors
Nao MD, Hokuto MEd, Takuya PhD, Nobuhiro PhD, Makoto PhD, Shunsuke PhD, Tatsuo MD, PhD, Mutsuko BSc, Shigaku MD, PhD, Hideoki MD, PhD, Ko MD, PhD, Chiharu PhD,