| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3198503 | Journal of Allergy and Clinical Immunology | 2012 | 27 Pages |
Abstract
This GWAS of the FHS cohort has identified genetic loci in HLA genes that might have a role in the pathogenesis of IgE dysregulation and atopy. It also confirmed the association of the known susceptibility loci FCER1A, STAT6, and IL13 for the dysregulation of total IgE.
Keywords
Stat6RAD50CEUFHScAMPTotal IgEAtopyAsthmaChildhood Asthma Management ProgramCooperative Health Research in the Region of AugsburgDARCLinkage disequilibriumSignal transducer and activator of transcription 6Framingham Heart StudyGenome-wide association studyGWASmAChSingle nucleotide polymorphismSNPKORA
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Authors
Mark MD, Jemma B. DSc, Marina MD, PhD, David P. MD, Stephan MD, Eva MSc, Christian PhD, Joachim PhD, Blanca E. PhD, Gary M. MD, MPH, Juan C. MD, DrPH, Scott T. MD, William W. PhD, Lindsay A. PhD, David M. MD, George T. MD, MS,